adisease

Showing entry for Severe depression

General Disease Information
BXGD Id	BXGD009620
Disease Name	Severe depression
Disease CUI Id	C0588008
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07108	BXGT006551	Acyl-CoA-binding protein	1622	reviewed	Enzyme modulator
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P34949	BXGT009775	Mannose-6-phosphate isomerase	4351	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q13554	BXGT013374	Calcium/calmodulin-dependent protein kinase type II subunit beta	816	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q86TM3	BXGT017607	Probable ATP-dependent RNA helicase DDX53	168400	reviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}