Showing entry for Interleukin-6 receptor subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006835
Protein NameInterleukin-6 receptor subunit alpha
Uniport IdP08887
GeneIL6R
Gene Id3570
Domainig; IL6Ra-bind
Pfam PF00047   PF09240  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor
3. Environmental Information Processing 3.2 Signal transduction hsa04066 HIF-1 signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04630 Jak-STAT signaling pathway
5. Organismal Systems 5.1 Immune system hsa04640 Hematopoietic cell lineage
5. Organismal Systems 5.1 Immune system hsa04659 Th17 cell differentiation
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.9 Infectious diseases: Viral hsa05163 Human cytomegalovirus infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006953 acute-phase response
Biological Process GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0050829 defense response to Gram-negative bacterium
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0031018 endocrine pancreas development
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0002384 hepatic immune response
Biological Process GO:0070102 interleukin-6-mediated signaling pathway
Biological Process GO:0002548 monocyte chemotaxis
Biological Process GO:0032966 negative regulation of collagen biosynthetic process
Biological Process GO:0032717 negative regulation of interleukin-8 production
Biological Process GO:0002446 neutrophil mediated immunity
Biological Process GO:0010536 positive regulation of activation of Janus kinase activity
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0072126 positive regulation of glomerular mesangial cell proliferation
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0002690 positive regulation of leukocyte chemotaxis
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045669 positive regulation of osteoblast differentiation
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0034097 response to cytokine
Biological Process GO:0072540 T-helper 17 cell lineage commitment
Biological Process GO:0010573 vascular endothelial growth factor production
molecular function GO:0070119 ciliary neurotrophic factor binding
molecular function GO:0019955 cytokine binding
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0019899 enzyme binding
molecular function GO:0019970 interleukin-11 binding
molecular function GO:0004921 interleukin-11 receptor activity
molecular function GO:0019981 interleukin-6 binding
molecular function GO:0004915 interleukin-6 receptor activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0070110 ciliary neurotrophic factor receptor complex
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005896 interleukin-6 receptor complex
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1059683 Interleukin-6 signaling
R-HSA-110056 MAPK3 (ERK1) activation
R-HSA-112409 RAF-independent MAPK1/3 activation
R-HSA-112411 MAPK1 (ERK2) activation
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-168256 Immune System
R-HSA-449147 Signaling by Interleukins
R-HSA-5663205 Infectious disease
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-6783589 Interleukin-6 family signaling
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-9616222 Transcriptional regulation of granulopoiesis
R-HSA-9679191 Potential therapeutics for SARS
R-HSA-9679506 SARS-CoV Infections
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001349 BXGD000044 Acute-Phase Reaction Pathological Conditions, Signs and Symptoms
C0001510 BXGD000057 Postoperative adhesion Pathological Conditions, Signs and Symptoms
C0001787 BXGD000076 Osteoporosis, Age-Related Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003507 BXGD000203 Aortic Valve Stenosis Cardiovascular Diseases
C0003615 BXGD000212 Appendicitis Digestive System Diseases; Infections
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007286 BXGD000459 Carpal Tunnel Syndrome Nervous System Diseases; Wounds and Injuries
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008313 BXGD000528 Cholangitis, Sclerosing Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009326 BXGD000598 Collagen Diseases Skin and Connective Tissue Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011206 BXGD000703 Delirium Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011311 BXGD000714 Dengue Fever Infections
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017531 BXGD001113 Angiolymphoid hyperplasia Immune System Diseases; Hemic and Lymphatic Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020502 BXGD001410 Hyperparathyroidism Endocrine System Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020725 BXGD001465 Type II Mucolipidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0021122 BXGD001481 Disruptive, Impulse Control, and Conduct Disorders Mental Disorders
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024440 BXGD001774 Macular Edema, Cystoid Eye Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024894 BXGD001810 Mastitis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C0024899 BXGD001812 Mastocytosis Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026470 BXGD001903 Monoclonal Gammopathy of Undetermined Significance Immune System Diseases; Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027873 BXGD002054 Neuromyelitis Optica Eye Diseases; Immune System Diseases; Nervous System Diseases
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029191 BXGD002122 Orchitis Male Urogenital Diseases; Endocrine System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029459 BXGD002159 Osteoporosis, Senile Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029882 BXGD002177 Otitis Media Otorhinolaryngologic Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030481 BXGD002228 Tropical Spastic Paraparesis Infections; Nervous System Diseases
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032131 BXGD002330 Plasmacytoma Neoplasms; Immune System Diseases
C0032533 BXGD002358 Polymyalgia Rheumatica Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034103 BXGD002464 Pulpitis Stomatognathic Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035435 BXGD002549 Rheumatism Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039263 BXGD002805 Takayasu Arteritis Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0039483 BXGD002813 Giant Cell Arteritis Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0040137 BXGD002846 Thyroid Nodule Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042165 BXGD002966 Anterior uveitis Eye Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0085693 BXGD003241 Acute appendicitis NOS (disorder) Digestive System Diseases; Infections
C0087031 BXGD003319 Juvenile-Onset Still Disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0154251 BXGD003710 Lipid Metabolism Disorders Nutritional and Metabolic Diseases
C0155880 BXGD003831 Intrinsic asthma Respiratory Tract Diseases; Immune System Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201657 BXGD004051 C-reactive protein measurement
C0202202 BXGD004082 Protein measurement
C0206081 BXGD004152 Hyperandrogenism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0206681 BXGD004236 Adenocarcinoma, Clear Cell Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0221014 BXGD004364 Reactive systemic amyloidosis Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0238281 BXGD004902 Middle Cerebral Artery Syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0238402 BXGD004924 Pycnodysostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0271051 BXGD006153 Macular retinal edema Eye Diseases
C0278486 BXGD006513 Breast cancer stage II
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0337428 BXGD007155 Fibrinogen assay
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339143 BXGD007226 Thyroid associated opthalmopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0340629 BXGD007354 Aortic aneurysm without mention of rupture NOS Cardiovascular Diseases
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0375021 BXGD007969 Human immunodeficiency virus, type 2 [HIV-2] infection in conditions classified elsewhere and of unspecified site
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0392885 BXGD008071 High density lipoprotein measurement
C0403601 BXGD008298 Transplant glomerulopathy
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0426576 BXGD008571 Gastrointestinal symptom Pathological Conditions, Signs and Symptoms
C0427460 BXGD008616 Red cell distribution width determination
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0588008 BXGD009620 Severe depression Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740376 BXGD009982 Middle Cerebral Artery Thrombosis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0741160 BXGD010025 Aortic Aneurysm, Ruptured Cardiovascular Diseases; Wounds and Injuries
C0741682 BXGD010039 Premenopausal breast cancer
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0751406 BXGD010428 Post-Traumatic Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0751845 BXGD010605 Middle Cerebral Artery Embolus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751846 BXGD010606 Left Middle Cerebral Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751847 BXGD010607 Embolic Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751848 BXGD010608 Thrombotic Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751849 BXGD010609 Right Middle Cerebral Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0858004 BXGD011168 Influenza A virus infection Infections; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1266042 BXGD011938 Chromophobe Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266043 BXGD011939 Sarcomatoid Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1266044 BXGD011940 Collecting Duct Carcinoma of the Kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1292753 BXGD012226 Primary Effusion Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1299433 BXGD012258 Left main coronary artery disease Cardiovascular Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1325327 BXGD012455 fibrinogen activity
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1334815 BXGD012743 Multi-centric Castleman's Disease Immune System Diseases; Hemic and Lymphatic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1384600 BXGD012945 Systemic onset juvenile chronic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C1392224 BXGD012976 Centrocytic lymphoma
C1519666 BXGD013240 Tumor-Associated Vasculature
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1531608 BXGD013299 Smoldering myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1561955 BXGD013367 Fibrinogen, CTCAE
C1608408 BXGD013434 Malignant transformation
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1704423 BXGD013559 Milroy Disease Hemic and Lymphatic Diseases
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1737250 BXGD013725 Progression of non-small cell lung cancer
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1842247 BXGD014508 CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1 Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1855020 BXGD015451 Acute necrotizing encephalopathy
C1858558 BXGD015806 Rheumatoid Arthritis, Systemic Juvenile Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2063866 BXGD016906 Depressive Disorder, Treatment-Resistant Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242712 BXGD016999 Hyper LDL cholesterolaemia
C2931171 BXGD017967 Juvenile pauciarticular chronic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3536715 BXGD019070 AA amyloidosis Nutritional and Metabolic Diseases
C3540094 BXGD019090 INTERLEUKIN 6, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS
C3553493 BXGD019176 SOLUBLE INTERLEUKIN-6 RECEPTOR, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS
C3714757 BXGD019430 Juvenile rheumatoid arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3839280 BXGD019772 High grade serous carcinoma
C3890205 BXGD020020 Polyarticular Juvenile Idiopathic Arthritis, Rheumatoid Factor Negative Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3897558 BXGD020048 Soluble Interleukin 6 Receptor Measurement
C3898105 BXGD020059 Oligoarticular Juvenile Idiopathic Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4255010 BXGD022310 Non-ST Elevated Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4520714 BXGD023034 Stage II Breast Cancer AJCC v6 and v7
C4521004 BXGD023054 Polyarticular juvenile idiopathic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4706387 BXGD023690 Acute necrotizing encephalopathy of childhood
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4749462 BXGD024060 New-onset refractory status epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006271 L-Cysteine 121.16
BXGC0018397 beta-1,4-mannan 180.06
BXGC0019164 Raloxifene 473.17
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein