Showing entry for Transcription elongation regulator 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004097
Protein NameTranscription elongation regulator 1
Uniport IdO14776
GeneTCERG1
Gene Id10915
DomainFF; WW
Pfam PF01846   PF00397  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.1 Transcription hsa03040 Spliceosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006397 mRNA processing
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
Biological Process GO:0008380 RNA splicing
molecular function GO:0042802 identical protein binding
molecular function GO:0070064 proline-rich region binding
molecular function GO:0003723 RNA binding
molecular function GO:0070063 RNA polymerase binding
molecular function GO:0001103 RNA polymerase II repressing transcription factor binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0003712 transcription coregulator activity
molecular function GO:0003714 transcription corepressor activity
molecular function GO:0003711 transcription elongation regulator activity
molecular function GO:0044390 ubiquitin-like protein conjugating enzyme binding
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C2718017 BXGD017522 TDP-43 Proteinopathies Nutritional and Metabolic Diseases; Nervous System Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein