Showing entry for Apoptosis regulatory protein Siva


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004151
Protein NameApoptosis regulatory protein Siva
Uniport IdO15304
GeneSIVA1
Gene Id10572
DomainSiva
Pfam PF05458  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04115 p53 signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006924 activation-induced cell death of T cells
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0097193 intrinsic apoptotic signaling pathway
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
molecular function GO:0005175 CD27 receptor binding
molecular function GO:0046872 metal ion binding
molecular function GO:0005164 tumor necrosis factor receptor binding
molecular function GO:0001618 virus receptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0010246 BXGD000656 Coxsackievirus Infections Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030201 BXGD002194 Pain, Postoperative Pathological Conditions, Signs and Symptoms
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein