Showing entry for Familial Mediterranean Fever


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002279
Disease NameFamilial Mediterranean Fever
Disease CUI IdC0031069
MeSH Codes C16  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630   DOID:7  
Disease Ontology Class Namedisease of metabolism; genetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15304 BXGT004151 Apoptosis regulatory protein Siva 10572 reviewed
O15553 BXGT004181 Pyrin 4210 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01031 BXGT005720 Complement C5 727 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04156 BXGT006156 Major prion protein 5621 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06126 BXGT006412 T-cell surface glycoprotein CD1a 909 reviewed
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29017 BXGT009305 T-cell surface glycoprotein CD1c 911 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P57764 BXGT011217 Gasdermin-D 79792 reviewed
P61626 BXGT011382 Lysozyme C 4069 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16512 BXGT013631 Serine/threonine-protein kinase N1 5585 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease