Showing entry for Aflatoxin B1 aldehyde reductase member 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005352
Protein NameAflatoxin B1 aldehyde reductase member 3
Uniport IdO95154
GeneAKR7A3
Gene Id22977
DomainAldo_ket_red
Pfam PF00248  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046223 aflatoxin catabolic process
Biological Process GO:0006081 cellular aldehyde metabolic process
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0004033 aldo-keto reductase (NADP) activity
molecular function GO:0009055 electron transfer activity
molecular function GO:0042802 identical protein binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-211859 Biological oxidations
R-HSA-5423646 Aflatoxin activation and detoxification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein