Showing entry for Hepatocarcinogenesis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013188
Disease NameHepatocarcinogenesis
Disease CUI IdC1512409
MeSH Codes C23   C04  
Disease Class NamePathological Conditions, Signs and Symptoms; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00255 BXGT003903 Menin 4221 reviewed
O00264 BXGT003904 Membrane-associated progesterone receptor component 1 10857 reviewed Signaling
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 10733 reviewed Kinase
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O14684 BXGT004082 Prostaglandin E synthase 9536 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O15169 BXGT004134 Axin-1 8312 reviewed
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43293 BXGT004584 Death-associated protein kinase 3 1613 reviewed Kinase
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43597 BXGT004602 Protein sprouty homolog 2 10253 reviewed Signaling
O43708 BXGT004617 Maleylacetoacetate isomerase 2954 reviewed
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60488 BXGT004878 Long-chain-fatty-acid--CoA ligase 4 2182 reviewed Enzyme
O60568 BXGT004885 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 8985 reviewed Enzyme
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75084 BXGT005098 Frizzled-7 8324 reviewed G-protein coupled receptor
O75367 BXGT005117 Core histone macro-H2A.1 9555 reviewed Nucleic acid binding
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O75663 BXGT005143 TIP41-like protein 261726 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95154 BXGT005352 Aflatoxin B1 aldehyde reductase member 3 22977 reviewed Enzyme
O95243 BXGT005362 Methyl-CpG-binding domain protein 4 8930 reviewed Enzyme
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 10298 reviewed Kinase
O96020 BXGT005416 G1/S-specific cyclin-E2 9134 reviewed Enzyme modulator
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05546 BXGT006367 Heparin cofactor 2 3053 reviewed Enzyme modulator
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08133 BXGT006727 Annexin A6 309 reviewed
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08758 BXGT006821 Annexin A5 308 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09455 BXGT006890 Retinol-binding protein 1 5947 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P16591 BXGT008246 Tyrosine-protein kinase Fer 2241 reviewed Kinase
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18283 BXGT008395 Glutathione peroxidase 2 2877 reviewed Enzyme
P18669 BXGT008419 Phosphoglycerate mutase 1 5223 reviewed
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P19801 BXGT008516 Amiloride-sensitive amine oxidase [copper-containing] 26 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22392 BXGT008762 Nucleoside diphosphate kinase B 654364 reviewed Kinase
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23396 BXGT008863 40S ribosomal protein S3 6188 reviewed Nucleic acid binding
P23468 BXGT008870 Receptor-type tyrosine-protein phosphatase delta 5789 reviewed Enzyme
P23526 BXGT008878 Adenosylhomocysteinase 191 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P24864 BXGT009000 G1/S-specific cyclin-E1 898 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29401 BXGT009344 Transketolase 7086 reviewed Enzyme
P29508 BXGT009358 Serpin B3 6317 reviewed Enzyme modulator
P30044 BXGT009395 Peroxiredoxin-5, mitochondrial 25824 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30153 BXGT009409 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 5518 reviewed Enzyme
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P31153 BXGT009512 S-adenosylmethionine synthase isoform type-2 4144 reviewed Enzyme
P31327 BXGT009523 Carbamoyl-phosphate synthase [ammonia], mitochondrial 1373 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 5105 reviewed Kinase
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36639 BXGT009930 7,8-dihydro-8-oxoguanine triphosphatase 4521 reviewed Enzyme
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P45973 BXGT010492 Chromobox protein homolog 5 23468 reviewed Epigenetic regulator
P45974 BXGT010493 Ubiquitin carboxyl-terminal hydrolase 5 8078 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46939 BXGT010555 Utrophin 7402 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 3094 reviewed Enzyme
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P50336 BXGT010791 Protoporphyrinogen oxidase 5498 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P51858 BXGT010900 Hepatoma-derived growth factor 3068 reviewed Signaling
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 5608 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P54687 BXGT011067 Branched-chain-amino-acid aminotransferase, cytosolic 586 reviewed Enzyme
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P60033 BXGT011286 CD81 antigen 975 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P61024 BXGT011350 Cyclin-dependent kinases regulatory subunit 1 1163 reviewed Enzyme modulator
P61088 BXGT011358 Ubiquitin-conjugating enzyme E2 N 7334 reviewed
P61964 BXGT011396 WD repeat-containing protein 5 11091 reviewed
P62805 BXGT011457 Histone H4 8370 reviewed
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P67775 BXGT011563 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 5515 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
P78563 BXGT011850 Double-stranded RNA-specific editase 1 104 reviewed Enzyme
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00266 BXGT012515 S-adenosylmethionine synthase isoform type-1 4143 reviewed Enzyme
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01082 BXGT012567 Spectrin beta chain, non-erythrocytic 1 6711 reviewed
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q02410 BXGT012652 Amyloid-beta A4 precursor protein-binding family A member 1 320 reviewed Transporter
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q04724 BXGT012778 Transducin-like enhancer protein 1 7088 reviewed Transcription factor
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q07157 BXGT012920 Tight junction protein ZO-1 7082 reviewed Cell-cell junction
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q12772 BXGT013262 Sterol regulatory element-binding protein 2 6721 reviewed
Q12923 BXGT013281 Tyrosine-protein phosphatase non-receptor type 13 5783 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13523 BXGT013368 Serine/threonine-protein kinase PRP4 homolog 8899 reviewed Kinase
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14011 BXGT013436 Cold-inducible RNA-binding protein 1153 reviewed Nucleic acid binding
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q14498 BXGT013475 RNA-binding protein 39 9584 reviewed
Q14749 BXGT013503 Glycine N-methyltransferase 27232 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14914 BXGT013513 Prostaglandin reductase 1 22949 reviewed Enzyme
Q14973 BXGT013515 Sodium/bile acid cotransporter 6554 reviewed Transporter
Q14978 BXGT013517 Nucleolar and coiled-body phosphoprotein 1 9221 reviewed
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 6195 reviewed Kinase
Q15493 BXGT013575 Regucalcin 9104 reviewed Enzyme
Q15554 BXGT013577 Telomeric repeat-binding factor 2 7014 reviewed
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q15599 BXGT013583 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 9351 reviewed
Q15788 BXGT013598 Nuclear receptor coactivator 1 8648 reviewed Kinase
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16706 BXGT013660 Alpha-mannosidase 2 4124 reviewed
Q16827 BXGT013675 Receptor-type tyrosine-protein phosphatase O 5800 reviewed
Q5HYI8 BXGT015421 Rab-like protein 3 285282 reviewed
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q7KZF4 BXGT016989 Staphylococcal nuclease domain-containing protein 1 27044 reviewed Transcription factor
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 415116 reviewed
Q86Z14 BXGT017639 Beta-klotho 152831 reviewed Enzyme
Q8IUQ4 BXGT018336 E3 ubiquitin-protein ligase SIAH1 6477 reviewed
Q8IV61 BXGT018340 Ras guanyl-releasing protein 3 25780 reviewed Enzyme modulator
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 22933 reviewed Epigenetic regulator
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92598 BXGT019356 Heat shock protein 105 kDa 10808 reviewed
Q92772 BXGT019371 Cyclin-dependent kinase-like 2 8999 reviewed Kinase
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92905 BXGT019393 COP9 signalosome complex subunit 5 10987 reviewed Enzyme
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q93088 BXGT019458 Betaine--homocysteine S-methyltransferase 1 635 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96FJ2 BXGT019659 Dynein light chain 2, cytoplasmic 140735 reviewed Cellular structure
Q96GX5 BXGT019668 Serine/threonine-protein kinase greatwall 84930 reviewed Kinase
Q96LA8 BXGT019691 Protein arginine N-methyltransferase 6 55170 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 79915 reviewed
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99496 BXGT019925 E3 ubiquitin-protein ligase RING2 6045 reviewed
Q99538 BXGT019931 Legumain 5641 reviewed Enzyme
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99704 BXGT019950 Docking protein 1 1796 reviewed
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BUP3 BXGT020137 Oxidoreductase HTATIP2 10553 reviewed
Q9BYT8 BXGT020190 Neurolysin, mitochondrial 57486 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H4B4 BXGT020474 Serine/threonine-protein kinase PLK3 1263 reviewed Kinase
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9NP72 BXGT021144 Ras-related protein Rab-18 22931 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NXA8 BXGT021245 NAD-dependent protein deacylase sirtuin-5, mitochondrial 23408 reviewed Epigenetic regulator
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NZI8 BXGT021273 Insulin-like growth factor 2 mRNA-binding protein 1 10642 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 51079 reviewed Enzyme
Q9P0U3 BXGT021292 Sentrin-specific protease 1 29843 reviewed Enzyme
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UI42 BXGT021713 Carboxypeptidase A4 51200 reviewed Enzyme
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UIK4 BXGT021720 Death-associated protein kinase 2 23604 reviewed Kinase
Q9UJ41 BXGT021723 Rab5 GDP/GTP exchange factor 27342 reviewed Enzyme modulator
Q9UJS0 BXGT021727 Calcium-binding mitochondrial carrier protein Aralar2 10165 reviewed Transporter
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9UQ84 BXGT021807 Exonuclease 1 9156 reviewed Enzyme
Q9Y230 BXGT022208 RuvB-like 2 10856 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y3B4 BXGT022255 Splicing factor 3B subunit 6 51639 reviewed
Q9Y3D8 BXGT022258 Adenylate kinase isoenzyme 6 102157402 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5S1 BXGT022300 Transient receptor potential cation channel subfamily V member 2 51393 reviewed Ion channel
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q9NSP4 BXGT022763 Centromere protein M 79019 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q9H8S9 BXGT023504 MOB kinase activator 1A 55233 reviewed Enzyme modulator
P56703 BXGT023722 Proto-oncogene Wnt-3 7473 reviewed Signaling
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q96RU2 BXGT024174 Ubiquitin carboxyl-terminal hydrolase 28 57646 reviewed Enzyme
P29590 BXGT024350 Protein PML 5371 reviewed
O43583 BXGT024866 Density-regulated protein 8562 reviewed Enzyme
Q9Y6M1 BXGT025468 Insulin-like growth factor 2 mRNA-binding protein 2 10644 reviewed Enzyme
Q96LR5 BXGT025885 Ubiquitin-conjugating enzyme E2 E2 7325 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease