Showing entry for Thioredoxin domain-containing protein 12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005405
Protein NameThioredoxin domain-containing protein 12
Uniport IdO95881
GeneTXNDC12
Gene Id51060
DomainThioredoxin_7
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.6 Metabolism of other amino acids hsa00480 Glutathione metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
molecular function GO:0015037 peptide disulfide oxidoreductase activity
molecular function GO:0019153 protein-disulfide reductase (glutathione) activity
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005788 endoplasmic reticulum lumen
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0008707 BXGD000565 Chronic osteomyelitis Infections; Musculoskeletal Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0279651 BXGD006674 Gallbladder adenocarcinoma Digestive System Diseases; Neoplasms
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein