adisease

Showing entry for Intelligence

General Disease Information
BXGD Id	BXGD001510
Disease Name	Intelligence
Disease CUI Id	C0021704
MeSH Codes	F01
Disease Class Name	Behavior and Behavior Mechanisms
Semantic Type	Mental Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A1Z1Q3	BXGT001069	ADP-ribose glycohydrolase MACROD2	140733	reviewed
O00481	BXGT003928	Butyrophilin subfamily 3 member A1	11119	reviewed	Enzyme modulator
O14929	BXGT004112	Histone acetyltransferase type B catalytic subunit	8520	reviewed	Enzyme
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15409	BXGT004166	Forkhead box protein P2	93986	reviewed
O43314	BXGT004585	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2	23262	reviewed
O43424	BXGT004592	Glutamate receptor ionotropic, delta-2	2895	reviewed	Ion channel
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43678	BXGT004613	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	4695	reviewed	Enzyme
O60307	BXGT004870	Microtubule-associated serine/threonine-protein kinase 3	23031	reviewed	Kinase
O75151	BXGT005103	Lysine-specific demethylase PHF2	5253	reviewed
O75746	BXGT005148	Calcium-binding mitochondrial carrier protein Aralar1	8604	reviewed	Transporter
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O95405	BXGT005379	Zinc finger FYVE domain-containing protein 9	9372	reviewed
O95793	BXGT005397	Double-stranded RNA-binding protein Staufen homolog 1	6780	reviewed
O95881	BXGT005405	Thioredoxin domain-containing protein 12	51060	reviewed	Enzyme
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P06681	BXGT006468	Complement C2	717	reviewed
P06732	BXGT006489	Creatine kinase M-type	1158	reviewed	Kinase
P08686	BXGT006813	Steroid 21-hydroxylase	1589	reviewed
P09958	BXGT006950	Furin	5045	reviewed	Enzyme
P10586	BXGT007581	Receptor-type tyrosine-protein phosphatase F	5792	reviewed	Enzyme
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10828	BXGT007624	Thyroid hormone receptor beta	7068	reviewed	Nuclear receptor
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P12277	BXGT007789	Creatine kinase B-type	1152	reviewed	Kinase
P13631	BXGT007929	Retinoic acid receptor gamma	5916	reviewed	Nuclear receptor
P13861	BXGT007961	cAMP-dependent protein kinase type II-alpha regulatory subunit	5576	reviewed
P15169	BXGT008093	Carboxypeptidase N catalytic chain	1369	reviewed
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P17050	BXGT008277	Alpha-N-acetylgalactosaminidase	4668	reviewed
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	6256	reviewed	Nuclear receptor
P19827	BXGT008523	Inter-alpha-trypsin inhibitor heavy chain H1	3697	reviewed	Enzyme modulator
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27816	BXGT009209	Microtubule-associated protein 4	4134	reviewed
P28066	BXGT009227	Proteasome subunit alpha type-5	5686	reviewed
P28347	BXGT009257	Transcriptional enhancer factor TEF-1	7003	reviewed	Transcription factor
P29320	BXGT009332	Ephrin type-A receptor 3	2042	reviewed	Kinase
P31323	BXGT009521	cAMP-dependent protein kinase type II-beta regulatory subunit	5577	reviewed
P32297	BXGT009616	Neuronal acetylcholine receptor subunit alpha-3	1136	reviewed	Ion channel
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P42858	BXGT010341	Huntingtin	3064	reviewed
P43115	BXGT010356	Prostaglandin E2 receptor EP3 subtype	5733	reviewed	G-protein coupled receptor
P43250	BXGT010372	G protein-coupled receptor kinase 6	2870	reviewed	Kinase
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	2555	reviewed	Ion channel
P48058	BXGT010614	Glutamate receptor 4	2893	reviewed	Ion channel
P48549	BXGT010644	G protein-activated inward rectifier potassium channel 1	3760	reviewed	Ion channel
P50225	BXGT010781	Sulfotransferase 1A1	6817	reviewed
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51957	BXGT010910	Serine/threonine-protein kinase Nek4	6787	reviewed	Kinase
P52756	BXGT010950	RNA-binding protein 5	10181	reviewed
P52803	BXGT010958	Ephrin-A5	1946	reviewed	Signaling
P53990	BXGT011024	IST1 homolog	9798	reviewed
P54619	BXGT011060	5'-AMP-activated protein kinase subunit gamma-1	5571	reviewed	Kinase
P54756	BXGT011074	Ephrin type-A receptor 5	2044	reviewed	Kinase
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61077	BXGT011355	Ubiquitin-conjugating enzyme E2 D3	7323	reviewed	Enzyme
P61586	BXGT011375	Transforming protein RhoA	387	reviewed	Enzyme modulator
P62491	BXGT011430	Ras-related protein Rab-11A	8766	reviewed
P62508	BXGT011431	Estrogen-related receptor gamma	2104	reviewed	Nuclear receptor
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63010	BXGT011484	AP-2 complex subunit beta	163	reviewed	Transporter
P63098	BXGT011497	Calcineurin subunit B type 1	5534	reviewed
P78317	BXGT011831	E3 ubiquitin-protein ligase RNF4	6047	reviewed
P78362	BXGT011839	SRSF protein kinase 2	6733	reviewed	Kinase
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q02224	BXGT012643	Centromere-associated protein E	1062	reviewed	Cellular structure
Q02410	BXGT012652	Amyloid-beta A4 precursor protein-binding family A member 1	320	reviewed	Transporter
Q08289	BXGT012979	Voltage-dependent L-type calcium channel subunit beta-2	783	reviewed	Ion channel
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q11203	BXGT013218	CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	6487	reviewed
Q12772	BXGT013262	Sterol regulatory element-binding protein 2	6721	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14123	BXGT013445	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	5137	reviewed
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14721	BXGT013502	Potassium voltage-gated channel subfamily B member 1	3745	reviewed	Ion channel
Q14832	BXGT013507	Metabotropic glutamate receptor 3	2913	reviewed	G-protein coupled receptor
Q14995	BXGT013520	Nuclear receptor subfamily 1 group D member 2	9975	reviewed	Nuclear receptor
Q15059	BXGT013530	Bromodomain-containing protein 3	8019	reviewed	Epigenetic regulator
Q15084	BXGT013536	Protein disulfide-isomerase A6	10130	reviewed
Q15139	BXGT013546	Serine/threonine-protein kinase D1	5587	reviewed	Kinase
Q15262	BXGT013555	Receptor-type tyrosine-protein phosphatase kappa	5796	reviewed	Enzyme
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15596	BXGT013582	Nuclear receptor coactivator 2	10499	reviewed	Enzyme
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15788	BXGT013598	Nuclear receptor coactivator 1	8648	reviewed	Kinase
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16706	BXGT013660	Alpha-mannosidase 2	4124	reviewed
Q16827	BXGT013675	Receptor-type tyrosine-protein phosphatase O	5800	reviewed
Q16874	BXGT013685	Cytochrome P450 21-hydroxylase	1589	unreviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q52WX2	BXGT014988	Serine/threonine-protein kinase SBK1	388228	reviewed
Q5TCY1	BXGT015853	Tau-tubulin kinase 1	84630	reviewed	Kinase
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6UWP2	BXGT016567	Dehydrogenase/reductase SDR family member 11	79154	reviewed	Enzyme
Q6UX04	BXGT016571	Spliceosome-associated protein CWC27 homolog	10283	reviewed	Enzyme
Q6V1X1	BXGT016574	Dipeptidyl peptidase 8	54878	reviewed	Enzyme
Q7KZF4	BXGT016989	Staphylococcal nuclease domain-containing protein 1	27044	reviewed	Transcription factor
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q86SR1	BXGT017600	Polypeptide N-acetylgalactosaminyltransferase 10	55568	reviewed	Enzyme
Q86U86	BXGT017611	Protein polybromo-1	55193	reviewed	Epigenetic regulator
Q8IU85	BXGT018333	Calcium/calmodulin-dependent protein kinase type 1D	57118	reviewed	Kinase
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8IWB6	BXGT018354	Inactive serine/threonine-protein kinase TEX14	56155	reviewed	Kinase
Q8IZS8	BXGT018372	Voltage-dependent calcium channel subunit alpha-2/delta-3	55799	reviewed	Ion channel
Q8N183	BXGT018497	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2	91942	reviewed
Q8NBQ5	BXGT018542	Estradiol 17-beta-dehydrogenase 11	51170	reviewed
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TCG2	BXGT018798	Phosphatidylinositol 4-kinase type 2-beta	55300	reviewed	Enzyme
Q8TEK3	BXGT018822	Histone-lysine N-methyltransferase, H3 lysine-79 specific	84444	reviewed	Epigenetic regulator
Q8TF61	BXGT018824	F-box only protein 41	150726	reviewed
Q8TF65	BXGT018825	PDZ domain-containing protein GIPC2	54810	reviewed	Enzyme
Q8WZA2	BXGT019025	Rap guanine nucleotide exchange factor 4	11069	reviewed	Enzyme modulator
Q92541	BXGT019353	RNA polymerase-associated protein RTF1 homolog	23168	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q92932	BXGT019395	Receptor-type tyrosine-protein phosphatase N2	5799	reviewed
Q96ES7	BXGT019654	SAGA-associated factor 29	112869	reviewed
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96GD3	BXGT019666	Polycomb protein SCMH1	22955	reviewed	Nucleic acid binding
Q96PR1	BXGT019710	Potassium voltage-gated channel subfamily C member 2	3747	reviewed	Ion channel
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q99829	BXGT019968	Copine-1	8904	reviewed
Q9BQE3	BXGT020109	Tubulin alpha-1C chain	84790	reviewed	Cellular structure
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9NPG3	BXGT021156	Ubinuclein-1	29855	reviewed
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9NSI6	BXGT021208	Bromodomain and WD repeat-containing protein 1	54014	reviewed
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9NY47	BXGT021249	Voltage-dependent calcium channel subunit alpha-2/delta-2	9254	reviewed	Ion channel
Q9NY59	BXGT021251	Sphingomyelin phosphodiesterase 3	55512	reviewed
Q9NZI8	BXGT021273	Insulin-like growth factor 2 mRNA-binding protein 1	10642	reviewed	Enzyme
Q9P0X4	BXGT021293	Voltage-dependent T-type calcium channel subunit alpha-1I	8911	reviewed	Ion channel
Q9UBG0	BXGT021654	C-type mannose receptor 2	9902	reviewed
Q9UH03	BXGT021690	Neuronal-specific septin-3	55964	reviewed	Enzyme modulator
Q9UL25	BXGT021753	Ras-related protein Rab-21	23011	reviewed
Q9UL54	BXGT021755	Serine/threonine-protein kinase TAO2	9344	reviewed	Kinase
Q9ULI0	BXGT021760	ATPase family AAA domain-containing protein 2B	54454	reviewed	Epigenetic regulator
Q9UQB8	BXGT021809	Brain-specific angiogenesis inhibitor 1-associated protein 2	10458	reviewed	Receptor
Q9Y2H9	BXGT022234	Microtubule-associated serine/threonine-protein kinase 1	22983	reviewed	Kinase
Q9Y2I1	BXGT022235	Nischarin	11188	reviewed	Enzyme modulator
Q9Y2T3	BXGT022246	Guanine deaminase	9615	reviewed	Enzyme
Q9Y3Q0	BXGT022263	N-acetylated-alpha-linked acidic dipeptidase 2	10003	reviewed	Enzyme
Q9Y4B6	BXGT022272	DDB1- and CUL4-associated factor 1	9730	reviewed
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
Q9Y5Z0	BXGT022310	Beta-secretase 2	25825	reviewed	Enzyme
Q9Y6E0	BXGT022327	Serine/threonine-protein kinase 24	8428	reviewed	Kinase
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q15878	BXGT022659	Voltage-dependent R-type calcium channel subunit alpha-1E	777	reviewed	Ion channel
F1T0I5	BXGT022675	Arylalkylamine N-acetyltransferase (Serotonin N-acetyltransferase)	15	unreviewed
Q5JP69	BXGT022691	C3/C5 convertase	717	unreviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
O15085	BXGT023125	Rho guanine nucleotide exchange factor 11	9826	reviewed
Q9BVI0	BXGT023340	PHD finger protein 20	51230	reviewed
O00308	BXGT023349	NEDD4-like E3 ubiquitin-protein ligase WWP2	11060	reviewed	Enzyme
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q9H2S1	BXGT023455	Small conductance calcium-activated potassium channel protein 2	3781	reviewed	Ion channel
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
P56703	BXGT023722	Proto-oncogene Wnt-3	7473	reviewed	Signaling
Q8TEP8	BXGT024036	Centrosomal protein of 192 kDa	55125	reviewed
Q9NVH0	BXGT024569	Exonuclease 3'-5' domain-containing protein 2	55218	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
O00409	BXGT024934	Forkhead box protein N3	1112	reviewed
Q9Y6M1	BXGT025468	Insulin-like growth factor 2 mRNA-binding protein 2	10644	reviewed	Enzyme
Q9UK61	BXGT025658	Protein TASOR	23272	reviewed
O43613	BXGT025666	Orexin receptor type 1	3061	reviewed	G-protein coupled receptor
Q96C45	BXGT025705	Serine/threonine-protein kinase ULK4	54986	reviewed	Kinase
Q7Z3B1	BXGT025707	Neuronal growth regulator 1	257194	reviewed
Q9P121	BXGT025711	Neurotrimin	50863	reviewed
O14917	BXGT025818	Protocadherin-17	27253	reviewed
A1L3X0	BXGT025992	Elongation of very long chain fatty acids protein 7	79993	reviewed	Enzyme
Q9BQ69	BXGT026098	ADP-ribose glycohydrolase MACROD1	28992	reviewed
Q7Z628	BXGT026116	Neuroepithelial cell-transforming gene 1 protein	10276	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}