protein

General Target Information
BXGT Id	BXGT006262
Protein Name	DNA topoisomerase 1
Uniport Id	P04786
Gene	TOP1
Gene Id	854156
Domain	Topoisom_I; Topoisom_I_N; Topo_C_assoc
Pfam	PF14370 PF01028 PF02919
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006333	chromatin assembly or disassembly
Biological Process	GO:0006338	chromatin remodeling
Biological Process	GO:0007059	chromosome segregation
Biological Process	GO:0006260	DNA replication
Biological Process	GO:0006271	DNA strand elongation involved in DNA replication
Biological Process	GO:0006265	DNA topological change
Biological Process	GO:0007076	mitotic chromosome condensation
Biological Process	GO:0007097	nuclear migration
Biological Process	GO:0000183	rDNA heterochromatin assembly
Biological Process	GO:0000019	regulation of mitotic recombination
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II
Biological Process	GO:0009303	rRNA transcription
Biological Process	GO:0006368	transcription elongation from RNA polymerase II promoter
molecular function	GO:0003677	DNA binding
molecular function	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity
cellular component	GO:0005730	nucleolus
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0005634	nucleus
cellular component	GO:0031298	replication fork protection complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}