Showing entry for Botulinum neurotoxin type B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007625
Protein NameBotulinum neurotoxin type B
Uniport IdP10844
GenebotB
Gene Id
Domain-
Pfam PF01742   PF07951   PF07953   PF07952  
OrganismClostridium botulinum
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046929 negative regulation of neurotransmitter secretion
Biological Process GO:0009405 pathogenesis
molecular function GO:0008289 lipid binding
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008320 protein transmembrane transporter activity
molecular function GO:0090729 toxin activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005576 extracellular region
cellular component GO:0044161 host cell cytoplasmic vesicle
cellular component GO:0044164 host cell cytosol
cellular component GO:0044156 host cell junction
cellular component GO:0044231 host cell presynaptic membrane
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-168799 Neurotoxicity of clostridium toxins
R-HSA-5250958 Toxicity of botulinum toxin type B (BoNT/B)
R-HSA-5339562 Uptake and actions of bacterial toxins
R-HSA-5663205 Infectious disease
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0005620 beta-D-Glucopyranose 180.16
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0027956 SHU 508 180.06
BXGC0034783 Doxorubicin 543.17
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein