Showing entry for cAMP-specific 3',5'-cyclic phosphodiesterase 4B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008035
Protein NamecAMP-specific 3',5'-cyclic phosphodiesterase 4B
Uniport IdP14646
GenePde4b
Gene Id24626
DomainPDE4_UCR; PDEase_I
Pfam PF18100   PF00233  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006198 cAMP catabolic process
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071872 cellular response to epinephrine stimulus
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0140199 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process
Biological Process GO:1901898 negative regulation of relaxation of cardiac muscle
Biological Process GO:0030593 neutrophil chemotaxis
Biological Process GO:0001780 neutrophil homeostasis
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0032743 positive regulation of interleukin-2 production
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:1901841 regulation of high voltage-gated calcium channel activity
Biological Process GO:0009408 response to heat
Biological Process GO:0050852 T cell receptor signaling pathway
molecular function GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
molecular function GO:0030552 cAMP binding
molecular function GO:0043015 gamma-tubulin binding
molecular function GO:0044325 ion channel binding
molecular function GO:0046872 metal ion binding
cellular component GO:0071944 cell periphery
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0060076 excitatory synapse
cellular component GO:0000930 gamma-tubulin complex
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0014069 postsynaptic density
cellular component GO:0008021 synaptic vesicle
cellular component GO:0005891 voltage-gated calcium channel complex
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0016090 Kurarinol 456.21
BXGC0019748 Kuraidin 438.2
BXGC0026947 (2R,3R)-2-(2,4-Dihydroxy-Phenyl)-3,7-Dihydroxy-8-(5-Hydroxy-2-Isopropenyl-5-Methyl-Hexyl)-5-Methoxy-Chroman-4-One 472.21
BXGC0028625 Sophoflavescenol 368.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein