Showing entry for Pancreatic triacylglycerol lipase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008208
Protein NamePancreatic triacylglycerol lipase
Uniport IdP16233
GenePNLIP
Gene Id5406
DomainLipase; PLAT
Pfam PF00151   PF01477  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00561 Glycerolipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
5. Organismal Systems 5.4 Digestive system hsa04975 Fat digestion and absorption
5. Organismal Systems 5.4 Digestive system hsa04977 Vitamin digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030299 intestinal cholesterol absorption
Biological Process GO:0016042 lipid catabolic process
Biological Process GO:0044241 lipid digestion
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0061365 positive regulation of triglyceride lipase activity
Biological Process GO:0001523 retinoid metabolic process
molecular function GO:0016298 lipase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004806 triglyceride lipase activity
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-162582 Signal Transduction
R-HSA-192456 Digestion of dietary lipid
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-2187338 Visual phototransduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-6806667 Metabolism of fat-soluble vitamins
R-HSA-8935690 Digestion
R-HSA-8963743 Digestion and absorption
R-HSA-975634 Retinoid metabolism and transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0038238 BXGD002741 Steatorrhea Digestive System Diseases; Nutritional and Metabolic Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0268240 BXGD005863 Pancreatic triacylglycerol lipase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C3280527 BXGD018835 PANCREATIC LIPASE DEFICIENCY
C4048329 BXGD021904 Immunosuppression
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001446 Koenigicine 323.39
BXGC0001448 Koenimbine 293.36
BXGC0001554 (+)-Mahanimbine 331.45
BXGC0002586 Calcium 40.08
BXGC0014308 ciwujianoside D2 1070.53
BXGC0022716 ciwujianoside C3 1058.57
BXGC0039306 Carnosic Acid 332.2
BXGC0041624 ciwujianoside C2 1216.59
BXGC0047442 Chiisanoside 954.48
BXGC0049297 Hederasaponin B 1204.62
BXGC0051734 Carnosol 330.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein