Showing entry for Acute pancreatitis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000041
Disease NameAcute pancreatitis
Disease CUI IdC0001339
MeSH Codes C06  
Disease Class NameDigestive System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0025031   HP:0002715  
Human Phenotype Ontology TermAbnormality of the digestive system; Abnormality of the immune system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15553 BXGT004181 Pyrin 4210 reviewed
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 8767 reviewed Kinase
O43603 BXGT004604 Galanin receptor type 2 8811 reviewed G-protein coupled receptor
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60755 BXGT004898 Galanin receptor type 3 8484 reviewed G-protein coupled receptor
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P07477 BXGT006629 Trypsin-1 5644 reviewed Enzyme
P07478 BXGT006630 Trypsin-2 5645 reviewed Enzyme
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08311 BXGT006762 Cathepsin G 1511 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09914 BXGT006940 Interferon-induced protein with tetratricopeptide repeats 1 3434 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12104 BXGT007773 Fatty acid-binding protein, intestinal 2169 reviewed
P12429 BXGT007814 Annexin A3 306 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15086 BXGT008078 Carboxypeptidase B 1360 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16233 BXGT008208 Pancreatic triacylglycerol lipase 5406 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P23526 BXGT008878 Adenosylhomocysteinase 191 reviewed Enzyme
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30405 BXGT009423 Peptidyl-prolyl cis-trans isomerase F, mitochondrial 10105 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32929 BXGT009682 Cystathionine gamma-lyase 1491 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35030 BXGT009784 Trypsin-3 5646 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35914 BXGT009880 Hydroxymethylglutaryl-CoA lyase, mitochondrial 3155 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41161 BXGT010229 ETS translocation variant 5 2119 reviewed Transcription factor
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46734 BXGT010537 Dual specificity mitogen-activated protein kinase kinase 3 5606 reviewed Kinase
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P54317 BXGT011045 Pancreatic lipase-related protein 2 5408 reviewed Enzyme
P54652 BXGT011064 Heat shock-related 70 kDa protein 2 3306 reviewed
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63244 BXGT011510 Receptor of activated protein C kinase 1 10399 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q08945 BXGT013014 FACT complex subunit SSRP1 6749 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14573 BXGT013486 Inositol 1,4,5-trisphosphate receptor type 3 3710 reviewed Ion channel
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15139 BXGT013546 Serine/threonine-protein kinase D1 5587 reviewed Kinase
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q53H47 BXGT015014 Histone-lysine N-methyltransferase SETMAR 6419 reviewed Epigenetic regulator
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 415116 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8NB16 BXGT018535 Mixed lineage kinase domain-like protein 197259 reviewed Kinase
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92772 BXGT019371 Cyclin-dependent kinase-like 2 8999 reviewed Kinase
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99784 BXGT019961 Noelin 10439 reviewed Cellular structure
Q99895 BXGT019974 Chymotrypsin-C 11330 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NRA0 BXGT021183 Sphingosine kinase 2 56848 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UL25 BXGT021753 Ras-related protein Rab-21 23011 reviewed
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y6X2 BXGT022343 E3 SUMO-protein ligase PIAS3 10401 reviewed
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
Q96BY9 BXGT025036 Store-operated calcium entry-associated regulatory factor 51669 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease