protein

Showing entry for Inter-alpha-trypsin inhibitor heavy chain H2

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT008522
Protein Name	Inter-alpha-trypsin inhibitor heavy chain H2
Uniport Id	P19823
Gene	ITIH2
Gene Id	3698
Domain	ITI_HC_C; VIT; VWA
Pfam	PF06668 PF08487 PF00092
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0044267	cellular protein metabolic process
Biological Process	GO:0030212	hyaluronan metabolic process
Biological Process	GO:0043687	post-translational protein modification
molecular function	GO:0004866	endopeptidase inhibitor activity
molecular function	GO:0004867	serine-type endopeptidase inhibitor activity
cellular component	GO:0072562	blood microparticle
cellular component	GO:0062023	collagen-containing extracellular matrix
cellular component	GO:0005788	endoplasmic reticulum lumen
cellular component	GO:0070062	extracellular exosome
cellular component	GO:0005576	extracellular region

Reactome

Pathway Id	Pathway Name
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-392499	Metabolism of proteins
R-HSA-597592	Post-translational protein modification
R-HSA-8957275	Post-translational protein phosphorylation

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0009319	BXGD000596	Colitis	Digestive System Diseases
C0021368	BXGD001502	Inflammation	Pathological Conditions, Signs and Symptoms
C0021390	BXGD001503	Inflammatory Bowel Diseases	Digestive System Diseases
C0022876	BXGD001591	Premature Obstetric Labor	Female Urogenital Diseases and Pregnancy Complications
C0271093	BXGD006162	Stargardt's disease
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0919267	BXGD011426	ovarian neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955	BXGD012005	Tumor Cell Invasion
C1845050	BXGD014703	PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2985280	BXGD018223	Blood Protein Measurement

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002616	Copper		63.55
BXGC0002682	Zinc		65.41

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}