Showing entry for PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD014703
Disease NamePIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS
Disease CUI IdC1845050
MeSH Codes C23   C16   C18   C17  
Disease Class NamePathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00451 BXGT003923 GDNF family receptor alpha-2 2675 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O15553 BXGT004181 Pyrin 4210 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02748 BXGT005940 Complement component C9 735 reviewed
P02750 BXGT005942 Leucine-rich alpha-2-glycoprotein 116844 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08047 BXGT006720 Transcription factor Sp1 6667 reviewed Nucleic acid binding
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09668 BXGT006914 Pro-cathepsin H 1512 reviewed Enzyme
P09884 BXGT006937 DNA polymerase alpha catalytic subunit 5422 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10745 BXGT007608 Retinol-binding protein 3 5949 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15336 BXGT008109 Cyclic AMP-dependent transcription factor ATF-2 1386 reviewed Transcription factor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P19823 BXGT008522 Inter-alpha-trypsin inhibitor heavy chain H2 3698 reviewed Enzyme modulator
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35613 BXGT009856 Basigin 682 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q07955 BXGT012951 Serine/arginine-rich splicing factor 1 6426 reviewed Nucleic acid binding
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15208 BXGT013550 Serine/threonine-protein kinase 38 11329 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BXJ0 BXGT020169 Complement C1q tumor necrosis factor-related protein 5 114902 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
Q86V25 BXGT024433 Tubulinyl-Tyr carboxypeptidase 2 79805 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease