protein

Showing entry for Sodium- and chloride-dependent GABA transporter 1

General Target Information
BXGT Id	BXGT008937
Protein Name	Sodium- and chloride-dependent GABA transporter 1
Uniport Id	P23978
Gene	Slc6a1
Gene Id	79212
Domain	SNF
Pfam	PF00209
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0008306	associative learning
Biological Process	GO:1902476	chloride transmembrane transport
Biological Process	GO:0051939	gamma-aminobutyric acid import
Biological Process	GO:0098658	inorganic anion import across plasma membrane
Biological Process	GO:0007612	learning
Biological Process	GO:0007613	memory
Biological Process	GO:0032229	negative regulation of synaptic transmission, GABAergic
Biological Process	GO:0098810	neurotransmitter reuptake
Biological Process	GO:0014054	positive regulation of gamma-aminobutyric acid secretion
Biological Process	GO:0051592	response to calcium ion
Biological Process	GO:0042220	response to cocaine
Biological Process	GO:0032355	response to estradiol
Biological Process	GO:0010035	response to inorganic substance
Biological Process	GO:0010288	response to lead ion
Biological Process	GO:0014070	response to organic cyclic compound
Biological Process	GO:0010033	response to organic substance
Biological Process	GO:0010243	response to organonitrogen compound
Biological Process	GO:0014074	response to purine-containing compound
Biological Process	GO:0009744	response to sucrose
Biological Process	GO:0009636	response to toxic substance
Biological Process	GO:0098719	sodium ion import across plasma membrane
Biological Process	GO:0050808	synapse organization
molecular function	GO:0005332	gamma-aminobutyric acid:sodium symporter activity
molecular function	GO:0042802	identical protein binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0042165	neurotransmitter binding
molecular function	GO:0015378	sodium:chloride symporter activity
cellular component	GO:0030424	axon
cellular component	GO:0009986	cell surface
cellular component	GO:0098982	GABA-ergic synapse
cellular component	GO:0099055	integral component of postsynaptic membrane
cellular component	GO:0099056	integral component of presynaptic membrane
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0043005	neuron projection
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0004665	4-Aminobutyric acid		103.12
BXGC0016891	Nortriptyline		263.17
BXGC0025862	Levothyroxine		776.69
BXGC0044598	Guvacine		127.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}