Showing entry for Glycylpeptide N-tetradecanoyltransferase 1



                       
General Target Information
BXGT IdBXGT009426
Protein NameGlycylpeptide N-tetradecanoyltransferase 1
Uniport IdP30419
GeneNMT1
Gene Id4836
DomainNMT; NMT_C
Pfam PF01233   PF02799  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042180 cellular ketone metabolic process
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0018008 N-terminal peptidyl-glycine N-myristoylation
Biological Process GO:0006499 N-terminal protein myristoylation
Biological Process GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
Biological Process GO:0022400 regulation of rhodopsin mediated signaling pathway
molecular function GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
molecular function GO:0019107 myristoyltransferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109581 Apoptosis
R-HSA-109606 Intrinsic Pathway for Apoptosis
R-HSA-162582 Signal Transduction
R-HSA-162587 HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-1643685 Disease
R-HSA-2187338 Visual phototransduction
R-HSA-2514856 The phototransduction cascade
R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-5357801 Programmed Cell Death
R-HSA-5663205 Infectious disease
R-HSA-75108 Activation, myristolyation of BID and translocation to mitochondria
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0005823 BXGD000339 Blood Pressure
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0024205 BXGD001744 Lymphadenitis Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026916 BXGD001947 Mycobacterium avium-intracellulare Infection Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0427460 BXGD008616 Red cell distribution width determination
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0871470 BXGD011316 Systolic Pressure
C1269955 BXGD012005 Tumor Cell Invasion
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C2931783 BXGD018061 Amelogenesis imperfecta nephrocalcinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Stomatognathic Diseases
C3714514 BXGD019409 Infection Infections
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0006198 Citric acid 192.12
BXGC0018063 Alprenolol 249.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein