protein

General Target Information
BXGT Id	BXGT009629
Protein Name	Serine/threonine-protein kinase/endoribonuclease IRE1
Uniport Id	P32361
Gene	IRE1
Gene Id	856478
Domain	Pkinase; Ribonuc_2-5A
Pfam	PF00069 PF06479
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0001300	chronological cell aging
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response
Biological Process	GO:0031505	fungal-type cell wall organization
Biological Process	GO:0006020	inositol metabolic process
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process	GO:0036498	IRE1-mediated unfolded protein response
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0034067	protein localization to Golgi apparatus
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:0036290	protein trans-autophosphorylation
Biological Process	GO:0034976	response to endoplasmic reticulum stress
molecular function	GO:0005524	ATP binding
molecular function	GO:0004521	endoribonuclease activity
molecular function	GO:0042802	identical protein binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004672	protein kinase activity
molecular function	GO:0004674	protein serine/threonine kinase activity
molecular function	GO:0051082	unfolded protein binding
cellular component	GO:0005783	endoplasmic reticulum
cellular component	GO:0005789	endoplasmic reticulum membrane
cellular component	GO:0030176	integral component of endoplasmic reticulum membrane
cellular component	GO:1990604	IRE1-TRAF2-ASK1 complex
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}