Showing entry for DNA damage-inducible transcript 3 protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009858
Protein NameDNA damage-inducible transcript 3 protein
Uniport IdP35639
GeneDdit3
Gene Id13198
Domain-
Pfam -  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0001955 blood vessel maturation
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response
Biological Process GO:0006983 ER overload response
Biological Process GO:0072655 establishment of protein localization to mitochondrion
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:1990442 intrinsic apoptotic signaling pathway in response to nitrosative stress
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0120163 negative regulation of cold-induced thermogenesis
Biological Process GO:0032792 negative regulation of CREB transcription factor activity
Biological Process GO:2000016 negative regulation of determination of dorsal identity
Biological Process GO:0043392 negative regulation of DNA binding
Biological Process GO:0043433 negative regulation of DNA-binding transcription factor activity
Biological Process GO:0045599 negative regulation of fat cell differentiation
Biological Process GO:0032689 negative regulation of interferon-gamma production
Biological Process GO:0032700 negative regulation of interleukin-17 production
Biological Process GO:0032713 negative regulation of interleukin-4 production
Biological Process GO:0045662 negative regulation of myoblast differentiation
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0034263 positive regulation of autophagy in response to ER overload
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0044324 regulation of transcription involved in anterior/posterior axis specification
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:0042594 response to starvation
Biological Process GO:0006986 response to unfolded protein
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0008140 cAMP response element binding protein binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0140416 DNA-binding transcription factor inhibitor activity
molecular function GO:0043522 leucine zipper domain binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
cellular component GO:1990622 CHOP-ATF3 complex
cellular component GO:1990617 CHOP-ATF4 complex
cellular component GO:0036488 CHOP-C/EBP complex
cellular component GO:0005737 cytoplasm
cellular component GO:0005770 late endosome
cellular component GO:0005634 nucleus
cellular component GO:0032993 protein-DNA complex
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001476 Girinimbine 263.33
BXGC0003255 Lochnocarpol A 408.49
BXGC0005319 Garcinone E 464.55
BXGC0009993 (R)-Mahanine 347.45
BXGC0019348 Angustibalin 304.13
BXGC0019377 Cumingianoside A 738.46
BXGC0020737 Protoapigenone 286.05
BXGC0020873 Aromaticin 246.13
BXGC0022273 4-Methylabyssinone V 422.21
BXGC0025757 Calcimycin 523.27
BXGC0035776 BRUCEOLIDE 438.15
BXGC0036860 Helenalin 262.12
BXGC0038486 (2S)-3-[(2S,3S)-5,7-Dihydroxy-2-(4-Methoxyphenyl)-4-Oxo-2,3-Dihydrochromen-3-Yl]-5,7-Dihydroxy-2-(4-Methoxyphenyl)-2,3-Dihydrochromen-4-One 570.15
BXGC0047086 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 281.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein