Showing entry for Adenylate cyclase type 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010160
Protein NameAdenylate cyclase type 8
Uniport IdP40146
GeneAdcy8
Gene Id29241
DomainAC_N; DUF1053; Guanylate_cyc
Pfam PF16214   PF06327   PF00211  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034199 activation of protein kinase A activity
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0006171 cAMP biosynthetic process
Biological Process GO:0019933 cAMP-mediated signaling
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:1904322 cellular response to forskolin
Biological Process GO:0071377 cellular response to glucagon stimulus
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0071315 cellular response to morphine
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0010255 glucose mediated signaling pathway
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0007616 long-term memory
Biological Process GO:0007613 memory
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0150076 neuroinflammatory response
Biological Process GO:0038003 opioid receptor signaling pathway
Biological Process GO:0032793 positive regulation of CREB transcription factor activity
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:1900454 positive regulation of long-term synaptic depression
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:0031915 positive regulation of synaptic plasticity
Biological Process GO:0051259 protein complex oligomerization
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0080135 regulation of cellular response to stress
Biological Process GO:0051480 regulation of cytosolic calcium ion concentration
Biological Process GO:0014070 response to organic cyclic compound
molecular function GO:0003779 actin binding
molecular function GO:0004016 adenylate cyclase activity
molecular function GO:0005524 ATP binding
molecular function GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0046872 metal ion binding
molecular function GO:0019902 phosphatase binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0046983 protein dimerization activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0047485 protein N-terminus binding
molecular function GO:0051721 protein phosphatase 2A binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005901 caveola
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0030665 clathrin-coated vesicle membrane
cellular component GO:0030425 dendrite
cellular component GO:0060076 excitatory synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0098686 hippocampal mossy fiber to CA3 synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0044853 plasma membrane raft
cellular component GO:0014069 postsynaptic density
cellular component GO:0048786 presynaptic active zone
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005871 Dopamine 153.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein