Showing entry for Matrix metalloproteinase-9



                       
General Target Information
BXGT IdBXGT010243
Protein NameMatrix metalloproteinase-9
Uniport IdP41245
GeneMmp9
Gene Id17395
Domainfn2; Hemopexin; Peptidase_M10; PG_binding_1; PT
Pfam PF00040   PF00045   PF00413   PF01471   PF04886  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0071460 cellular response to cell-matrix adhesion
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0071492 cellular response to UV-A
Biological Process GO:0030574 collagen catabolic process
Biological Process GO:0007566 embryo implantation
Biological Process GO:0035987 endodermal cell differentiation
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0007507 heart development
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:2001258 negative regulation of cation channel activity
Biological Process GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Biological Process GO:2000697 negative regulation of epithelial cell differentiation involved in kidney development
Biological Process GO:0048147 negative regulation of fibroblast proliferation
Biological Process GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0043388 positive regulation of DNA binding
Biological Process GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:0051549 positive regulation of keratinocyte migration
Biological Process GO:0002687 positive regulation of leukocyte migration
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:1900122 positive regulation of receptor binding
Biological Process GO:0090200 positive regulation of release of cytochrome c from mitochondria
Biological Process GO:0031915 positive regulation of synaptic plasticity
Biological Process GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
Biological Process GO:0006508 proteolysis
Biological Process GO:1904645 response to amyloid-beta
Biological Process GO:0042493 response to drug
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0001501 skeletal system development
Biological Process GO:0048771 tissue remodeling
Biological Process GO:0019087 transformation of host cell by virus
molecular function GO:0004175 endopeptidase activity
molecular function GO:0001968 fibronectin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0008233 peptidase activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004252 serine-type endopeptidase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0005615 extracellular space
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004560 Benzoic acid 122.12
BXGC0019419 2-hydroxypyridine 95.04
BXGC0042270 acetohydroxamic acid 75.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein