Showing entry for Folate receptor gamma


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010260
Protein NameFolate receptor gamma
Uniport IdP41439
GeneFOLR3
Gene Id2352
DomainFolate_rec
Pfam PF03024  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01523 Antifolate resistance
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0015884 folic acid transport
Biological Process GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0035036 sperm-egg recognition
molecular function GO:0005542 folic acid binding
molecular function GO:0038023 signaling receptor activity
cellular component GO:0031362 anchored component of external side of plasma membrane
cellular component GO:0005576 extracellular region
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0016020 membrane
cellular component GO:0035580 specific granule lumen
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0025312 BXGD001861 Meningomyelocele Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0007530 Folic acid 441.4
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein