Showing entry for NAD-dependent protein deacetylase HST2



                       
General Target Information
BXGT IdBXGT011011
Protein NameNAD-dependent protein deacetylase HST2
Uniport IdP53686
GeneHST2
Gene Id856092
DomainSIR2
Pfam PF02146  
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070933 histone H4 deacetylation
Biological Process GO:0031939 negative regulation of chromatin silencing at telomere
Biological Process GO:0045950 negative regulation of mitotic recombination
Biological Process GO:0000183 rDNA heterochromatin assembly
molecular function GO:0070403 NAD+ binding
molecular function GO:0017136 NAD-dependent histone deacetylase activity
molecular function GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
molecular function GO:0016740 transferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0006125 Nicotinamide 122.12
BXGC0016637 6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Ol 193.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein