Showing entry for cAMP-specific 3',5'-cyclic phosphodiesterase 4A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011071
Protein NamecAMP-specific 3',5'-cyclic phosphodiesterase 4A
Uniport IdP54748
GenePde4a
Gene Id25638
DomainPDE4_UCR; PDEase_I
Pfam PF18100   PF00233  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006198 cAMP catabolic process
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0043949 regulation of cAMP-mediated signaling
Biological Process GO:0010738 regulation of protein kinase A signaling
Biological Process GO:0042493 response to drug
Biological Process GO:0007608 sensory perception of smell
Biological Process GO:0007165 signal transduction
molecular function GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
molecular function GO:0030552 cAMP binding
molecular function GO:0046872 metal ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0016090 Kurarinol 456.21
BXGC0019748 Kuraidin 438.2
BXGC0026947 (2R,3R)-2-(2,4-Dihydroxy-Phenyl)-3,7-Dihydroxy-8-(5-Hydroxy-2-Isopropenyl-5-Methyl-Hexyl)-5-Methoxy-Chroman-4-One 472.21
BXGC0028625 Sophoflavescenol 368.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein