Showing entry for Glutathione peroxidase 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011278
Protein NameGlutathione peroxidase 6
Uniport IdP59796
GeneGPX6
Gene Id257202
DomainGSHPx
Pfam PF00255  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.6 Metabolism of other amino acids hsa00480 Glutathione metabolism
1. Metabolism 1.3 Lipid metabolism hsa00590 Arachidonic acid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
5. Organismal Systems 5.2 Endocrine system hsa04918 Thyroid hormone synthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006979 response to oxidative stress
molecular function GO:0004602 glutathione peroxidase activity
molecular function GO:0004601 peroxidase activity
cellular component GO:0005576 extracellular region
Reactome
Pathway Id Pathway Name
R-HSA-2262752 Cellular responses to stress
R-HSA-3299685 Detoxification of Reactive Oxygen Species
R-HSA-8953897 Cellular responses to external stimuli
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein