Showing entry for Lysine-specific demethylase 2A



                       
General Target Information
BXGT IdBXGT011282
Protein NameLysine-specific demethylase 2A
Uniport IdP59997
GeneKdm2a
Gene Id225876
DomainF-box; JHD; PHD_4; zf-CXXC
Pfam PF00646   PF17811   PF16866   PF02008  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0001947 heart looping
Biological Process GO:0070544 histone H3-K36 demethylation
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0010944 negative regulation of transcription by competitive promoter binding
Biological Process GO:0001843 neural tube closure
Biological Process GO:0060563 neuroepithelial cell differentiation
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0033184 positive regulation of histone ubiquitination
Biological Process GO:0042752 regulation of circadian rhythm
molecular function GO:0051864 histone demethylase activity (H3-K36 specific)
molecular function GO:0045322 unmethylated CpG binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001380 Succinic acid 118.09
BXGC0002485 2-Oxopentanedioic acid 146.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein