Showing entry for Voltage-dependent L-type calcium channel subunit alpha-1C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012619
Protein NameVoltage-dependent L-type calcium channel subunit alpha-1C
Uniport IdQ01815
GeneCacna1c
Gene Id12288
DomainCAC1F_C; Ca_chan_IQ; GPHH; Ion_trans
Pfam PF08763   PF16885   PF16905   PF00520  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0070509 calcium ion import
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0060402 calcium ion transport into cytosol
Biological Process GO:0043010 camera-type eye development
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0086002 cardiac muscle cell action potential involved in contraction
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0035115 embryonic forelimb morphogenesis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0030252 growth hormone secretion
Biological Process GO:0007507 heart development
Biological Process GO:0002520 immune system development
Biological Process GO:0030073 insulin secretion
Biological Process GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential
Biological Process GO:0086045 membrane depolarization during AV node cell action potential
Biological Process GO:0086012 membrane depolarization during cardiac muscle cell action potential
Biological Process GO:0045762 positive regulation of adenylate cyclase activity
Biological Process GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
Biological Process GO:0086091 regulation of heart rate by cardiac conduction
Biological Process GO:0046620 regulation of organ growth
Biological Process GO:0019229 regulation of vasoconstriction
Biological Process GO:0098911 regulation of ventricular cardiac muscle cell action potential
Biological Process GO:0006939 smooth muscle contraction
Biological Process GO:0060083 smooth muscle contraction involved in micturition
Biological Process GO:0008542 visual learning
molecular function GO:0051393 alpha-actinin binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0019899 enzyme binding
molecular function GO:0008331 high voltage-gated calcium channel activity
molecular function GO:0044325 ion channel binding
molecular function GO:0046872 metal ion binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0051721 protein phosphatase 2A binding
molecular function GO:0031369 translation initiation factor binding
molecular function GO:0005245 voltage-gated calcium channel activity
molecular function GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential
molecular function GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential
molecular function GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0002095 caveolar macromolecular signaling complex
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0043198 dendritic shaft
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:1990454 L-type voltage-gated calcium channel complex
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0042383 sarcolemma
cellular component GO:0030315 T-tubule
cellular component GO:0005891 voltage-gated calcium channel complex
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024988 Nifedipine 346.12
BXGC0052878 Bisphenol A 228.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein