Showing entry for N-arachidonyl glycine receptor



                       
General Target Information
BXGT IdBXGT013461
Protein NameN-arachidonyl glycine receptor
Uniport IdQ14330
GeneGPR18
Gene Id2841
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation
Biological Process GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0002689 negative regulation of leukocyte chemotaxis
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0035025 positive regulation of Rho protein signal transduction
molecular function GO:0004930 G protein-coupled receptor activity
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026618 BXGD001909 Dental Fluorosis, Acquired Stomatognathic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0741949 BXGD010047 Cardiovascular Pathology
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2745963 BXGD017571 Kashin-Beck Disease Musculoskeletal Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3665629 BXGD019297 Dental fluorosis
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000664 Maxepa 314.46
BXGC0040150 Cannabidiol 314.22
BXGC0053584 Emindole Sb 405.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein