Showing entry for Intraocular pressure disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009626
Disease NameIntraocular pressure disorder
Disease CUI IdC0595921
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00311 BXGT003908 Cell division cycle 7-related protein kinase 8317 reviewed Kinase
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O43143 BXGT004571 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 1665 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O95069 BXGT005348 Potassium channel subfamily K member 2 3776 reviewed Ion channel
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P16109 BXGT008194 P-selectin 6403 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P17707 BXGT008331 S-adenosylmethionine decarboxylase proenzyme 262 reviewed Enzyme
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35408 BXGT009828 Prostaglandin E2 receptor EP4 subtype 5734 reviewed G-protein coupled receptor
P35442 BXGT009832 Thrombospondin-2 7058 reviewed
P35580 BXGT009853 Myosin-10 4628 reviewed
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P43116 BXGT010357 Prostaglandin E2 receptor EP2 subtype 5732 reviewed G-protein coupled receptor
P43378 BXGT010383 Tyrosine-protein phosphatase non-receptor type 9 5780 reviewed Enzyme
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P45984 BXGT010495 Mitogen-activated protein kinase 9 5601 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase 22978 reviewed Enzyme
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50542 BXGT010808 Peroxisomal targeting signal 1 receptor 5830 reviewed Transporter
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P51884 BXGT010903 Lumican 4060 reviewed
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54289 BXGT011040 Voltage-dependent calcium channel subunit alpha-2/delta-1 781 reviewed Ion channel
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q12913 BXGT013279 Receptor-type tyrosine-protein phosphatase eta 5795 reviewed Enzyme
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13698 BXGT013392 Voltage-dependent L-type calcium channel subunit alpha-1S 779 reviewed Ion channel
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14330 BXGT013461 N-arachidonyl glycine receptor 2841 reviewed G-protein coupled receptor
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15077 BXGT013533 P2Y purinoceptor 6 5031 reviewed G-protein coupled receptor
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15717 BXGT013589 ELAV-like protein 1 1994 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q6IB77 BXGT016325 Glycine N-acyltransferase 10249 reviewed
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92959 BXGT019400 Solute carrier organic anion transporter family member 2A1 6578 reviewed Transporter
Q93062 BXGT019456 RNA-binding protein with multiple splicing 11030 reviewed Nucleic acid binding
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H816 BXGT020494 5' exonuclease Apollo 64858 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9HD67 BXGT020544 Unconventional myosin-X 4651 reviewed
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
Q96Q15 BXGT025610 Serine/threonine-protein kinase SMG1 23049 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease