Showing entry for ATP-dependent RNA helicase DHX8



                       
General Target Information
BXGT IdBXGT013483
Protein NameATP-dependent RNA helicase DHX8
Uniport IdQ14562
GeneDHX8
Gene Id1659
DomainHA2; Helicase_C; OB_NTP_bind; S1
Pfam PF04408   PF00271   PF07717   PF00575  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.1 Transcription hsa03040 Spliceosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0006396 RNA processing
Biological Process GO:0008380 RNA splicing
Biological Process GO:0000390 spliceosomal complex disassembly
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0003723 RNA binding
molecular function GO:0003724 RNA helicase activity
cellular component GO:0071013 catalytic step 2 spliceosome
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005681 spliceosomal complex
cellular component GO:0071007 U2-type catalytic step 2 spliceosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0677776 BXGD009728 Hereditary Breast and Ovarian Cancer Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein