Showing entry for Next to BRCA1 gene 1 protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013488
Protein NameNext to BRCA1 gene 1 protein
Uniport IdQ14596
GeneNBR1
Gene Id4077
DomainN_BRCA1_IG; PB1; ZZ
Pfam PF16158   PF00564   PF00569  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016236 macroautophagy
Biological Process GO:0045668 negative regulation of osteoblast differentiation
Biological Process GO:0030500 regulation of bone mineralization
Biological Process GO:0032872 regulation of stress-activated MAPK cascade
molecular function GO:0051019 mitogen-activated protein kinase binding
molecular function GO:0043130 ubiquitin binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005776 autophagosome
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005770 late endosome
cellular component GO:0005764 lysosome
cellular component GO:0031430 M band
cellular component GO:0016020 membrane
cellular component GO:0005758 mitochondrial intermembrane space
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
cellular component GO:0000407 phagophore assembly site
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1632852 Macroautophagy
R-HSA-1632852 Macroautophagy
R-HSA-9612973 Autophagy
R-HSA-9612973 Autophagy
R-HSA-9663891 Selective autophagy
R-HSA-9663891 Selective autophagy
R-HSA-9664873 Pexophagy
R-HSA-9664873 Pexophagy
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010246 BXGD000656 Coxsackievirus Infections Infections
C0014378 BXGD000912 Enterovirus Infections Infections
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0751713 BXGD010564 Inclusion Body Myopathy, Sporadic Musculoskeletal Diseases; Nervous System Diseases
C0751781 BXGD010590 Dentatorubral-Pallidoluysian Atrophy Nervous System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein