adisease

Showing entry for Dentatorubral-Pallidoluysian Atrophy

General Disease Information
BXGD Id	BXGD010590
Disease Name	Dentatorubral-Pallidoluysian Atrophy
Disease CUI Id	C0751781
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00142	BXGT003883	Thymidine kinase 2, mitochondrial	7084	reviewed	Kinase
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	8767	reviewed	Kinase
O95278	BXGT005370	Laforin	7957	reviewed
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04156	BXGT006156	Major prion protein	5621	reviewed
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05129	BXGT006322	Protein kinase C gamma type	5582	reviewed	Kinase
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07148	BXGT006559	Fatty acid-binding protein, liver	2168	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42858	BXGT010341	Huntingtin	3064	reviewed
P48547	BXGT010643	Potassium voltage-gated channel subfamily C member 1	3746	reviewed	Ion channel
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P63165	BXGT011506	Small ubiquitin-related modifier 1	7341	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q01118	BXGT012570	Sodium channel protein type 7 subunit alpha	6332	reviewed	Ion channel
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14596	BXGT013488	Next to BRCA1 gene 1 protein	4077	reviewed
Q14643	BXGT013493	Inositol 1,4,5-trisphosphate receptor type 1	3708	reviewed	Ion channel
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99574	BXGT019936	Neuroserpin	5274	reviewed	Enzyme modulator
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9NZJ4	BXGT021274	Sacsin	26278	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q9Y4W6	BXGT025025	AFG3-like protein 2	10939	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}