Showing entry for ATP-dependent Clp protease proteolytic subunit, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013664
Protein NameATP-dependent Clp protease proteolytic subunit, mitochondrial
Uniport IdQ16740
GeneCLPP
Gene Id8192
DomainCLP_protease
Pfam PF00574  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033619 membrane protein proteolysis
Biological Process GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Biological Process GO:0051603 proteolysis involved in cellular protein catabolic process
molecular function GO:0051117 ATPase binding
molecular function GO:0004176 ATP-dependent peptidase activity
molecular function GO:0004175 endopeptidase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0008233 peptidase activity
molecular function GO:0004252 serine-type endopeptidase activity
cellular component GO:0009368 endopeptidase Clp complex
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0232939 BXGD004568 Primary physiologic amenorrhea Pathological Conditions, Signs and Symptoms
C0266399 BXGD005663 Infantile uterus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271829 BXGD006267 Pendred's syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Endocrine System Diseases; Otorhinolaryngologic Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0685838 BXGD009820 Gonadal dysgenesis XX type deafness Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases; Endocrine System Diseases; Otorhinolaryngologic Diseases
C0747102 BXGD010159 Ovarian failure Endocrine System Diseases
C0751651 BXGD010539 Mitochondrial Diseases Nutritional and Metabolic Diseases
C0948896 BXGD011563 Primary hypogonadism Endocrine System Diseases
C1285498 BXGD012171 Vegetation
C1401084 BXGD013014 Ovarian Insufficiency
C1838180 BXGD014300 CODAS syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1865866 BXGD016345 Congenital sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C3532239 BXGD019055 Mitochondrial cardiomyopathy
C3554105 BXGD019200 PERRAULT SYNDROME 2
C3808414 BXGD019547 PERRAULT SYNDROME 3
C3809105 BXGD019573 PERRAULT SYNDROME 4
C4551721 BXGD023401 PERRAULT SYNDROME 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases; Endocrine System Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0042315 1,4-dioxane 88.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein