Showing entry for Adenosine receptor A2b



                       
General Target Information
BXGT IdBXGT015991
Protein NameAdenosine receptor A2b
Uniport IdQ60614
GeneAdora2b
Gene Id11541
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0031668 cellular response to extracellular stimulus
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0032966 negative regulation of collagen biosynthetic process
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0043950 positive regulation of cAMP-mediated signaling
Biological Process GO:0033605 positive regulation of catecholamine secretion
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010753 positive regulation of cGMP-mediated signaling
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0031284 positive regulation of guanylate cyclase activity
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0043306 positive regulation of mast cell degranulation
Biological Process GO:0010701 positive regulation of norepinephrine secretion
Biological Process GO:0010893 positive regulation of steroid biosynthetic process
Biological Process GO:0010575 positive regulation of vascular endothelial growth factor production
Biological Process GO:0010906 regulation of glucose metabolic process
Biological Process GO:0060087 relaxation of vascular associated smooth muscle
Biological Process GO:1990776 response to angiotensin
molecular function GO:0001609 G protein-coupled adenosine receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
cellular component GO:0009986 cell surface
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000204 Theophylline 180.16
BXGC0001502 Caffeine 194.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein