Showing entry for Bile acid receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015992
Protein NameBile acid receptor
Uniport IdQ60641
GeneNr1h4
Gene Id20186
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008206 bile acid metabolic process
Biological Process GO:0038183 bile acid signaling pathway
Biological Process GO:0007043 cell-cell junction assembly
Biological Process GO:0030154 cell differentiation
Biological Process GO:0001678 cellular glucose homeostasis
Biological Process GO:1903413 cellular response to bile acid
Biological Process GO:0071398 cellular response to fatty acid
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071417 cellular response to organonitrogen compound
Biological Process GO:0035356 cellular triglyceride homeostasis
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0055089 fatty acid homeostasis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0034971 histone H3-R17 methylation
Biological Process GO:0006954 inflammatory response
Biological Process GO:0045087 innate immune response
Biological Process GO:0032620 interleukin-17 production
Biological Process GO:0038185 intracellular bile acid receptor signaling pathway
Biological Process GO:0030522 intracellular receptor signaling pathway
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032966 negative regulation of collagen biosynthetic process
Biological Process GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0032689 negative regulation of interferon-gamma production
Biological Process GO:0032692 negative regulation of interleukin-1 production
Biological Process GO:0032703 negative regulation of interleukin-2 production
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0071638 negative regulation of monocyte chemotactic protein-1 production
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0010868 negative regulation of triglyceride biosynthetic process
Biological Process GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:1904468 negative regulation of tumor necrosis factor secretion
Biological Process GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling
Biological Process GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter
Biological Process GO:0007219 Notch signaling pathway
Biological Process GO:1904179 positive regulation of adipose tissue development
Biological Process GO:2001250 positive regulation of ammonia assimilation cycle
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:2000213 positive regulation of glutamate metabolic process
Biological Process GO:0046628 positive regulation of insulin receptor signaling pathway
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:1905695 positive regulation of phosphatidic acid biosynthetic process
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006109 regulation of carbohydrate metabolic process
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:0010988 regulation of low-density lipoprotein particle clearance
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0034255 regulation of urea metabolic process
Biological Process GO:0071873 response to norepinephrine
Biological Process GO:0034142 toll-like receptor 4 signaling pathway
Biological Process GO:0034162 toll-like receptor 9 signaling pathway
Biological Process GO:0070328 triglyceride homeostasis
molecular function GO:0032052 bile acid binding
molecular function GO:0038181 bile acid receptor activity
molecular function GO:1902122 chenodeoxycholic acid binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0042277 peptide binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046965 retinoid X receptor binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0042025 host cell nucleus
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005719 nuclear euchromatin
cellular component GO:0005634 nucleus
cellular component GO:0043235 receptor complex
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001030 Artemetin 388.37
BXGC0001875 Chalepin acetate 356.41
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0022231 Ursodiol 392.29
BXGC0044468 Ergosterol Peroxide 428.33
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein