Showing entry for 5-hydroxytryptamine receptor 1A



                       
General Target Information
BXGT IdBXGT016110
Protein Name5-hydroxytryptamine receptor 1A
Uniport IdQ64264
GeneHtr1a
Gene Id15550
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0035640 exploration behavior
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0014053 negative regulation of gamma-aminobutyric acid secretion
Biological Process GO:0097114 NMDA glutamate receptor clustering
Biological Process GO:0031117 positive regulation of microtubule depolymerization
Biological Process GO:0042053 regulation of dopamine metabolic process
Biological Process GO:0060259 regulation of feeding behavior
Biological Process GO:0046883 regulation of hormone secretion
Biological Process GO:0014062 regulation of serotonin secretion
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0042428 serotonin metabolic process
Biological Process GO:0007210 serotonin receptor signaling pathway
Biological Process GO:0042310 vasoconstriction
molecular function GO:0008144 drug binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0090722 receptor-receptor interaction
molecular function GO:0051378 serotonin binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0043203 axon hillock
cellular component GO:0030425 dendrite
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005867 Serotonin 176.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein