Showing entry for All-trans-retinol 13,14-reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016430
Protein NameAll-trans-retinol 13,14-reductase
Uniport IdQ6NUM9
GeneRETSAT
Gene Id54884
DomainNAD_binding_8
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00830 Retinol metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0042572 retinol metabolic process
molecular function GO:0051786 all-trans-retinol 13,14-reductase activity
molecular function GO:0016491 oxidoreductase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016020 membrane
cellular component GO:0031965 nuclear membrane
cellular component GO:0005640 nuclear outer membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-162582 Signal Transduction
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-2187338 Visual phototransduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-6806667 Metabolism of fat-soluble vitamins
R-HSA-975634 Retinoid metabolism and transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0796154 BXGD010805 SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases; Mental Disorders; Behavior and Behavior Mechanisms; Cardiovascular Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047568 Retinol 286.23
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein