adisease

General Disease Information
BXGD Id	BXGD010805
Disease Name	SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1
Disease CUI Id	C0796154
MeSH Codes	C23 C16 C05 C10 C19 F03 F01 C14
Disease Class Name	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases; Mental Disorders; Behavior and Behavior Mechanisms; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P16070	BXGT008186	CD44 antigen	960	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P35052	BXGT009788	Glypican-1	2817	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16666	BXGT013654	Gamma-interferon-inducible protein 16	3428	reviewed	Transcription factor
Q6NUM9	BXGT016430	All-trans-retinol 13,14-reductase	54884	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}