Showing entry for Lethal(2) giant larvae protein homolog 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016444
Protein NameLethal(2) giant larvae protein homolog 2
Uniport IdQ6P1M3
GeneLLGL2
Gene Id3993
DomainLLGL; WD40
Pfam PF08366   PF00400  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0030866 cortical actin cytoskeleton organization
Biological Process GO:0051294 establishment of spindle orientation
Biological Process GO:0006887 exocytosis
Biological Process GO:0015820 leucine transport
Biological Process GO:0032878 regulation of establishment or maintenance of cell polarity
Biological Process GO:0008593 regulation of Notch signaling pathway
Biological Process GO:0050708 regulation of protein secretion
molecular function GO:0005096 GTPase activator activity
molecular function GO:0045159 myosin II binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0017137 Rab GTPase binding
cellular component GO:0030864 cortical actin cytoskeleton
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014772 BXGD000948 Red Blood Cell Count measurement
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0016529 BXGD001068 Forced expiratory volume function
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0042834 BXGD003004 Vital capacity
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0267111 BXGD005732 Gastric dysplasia Digestive System Diseases; Neoplasms
C0334037 BXGD006980 Intestinal metaplasia
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein