Showing entry for DNA cross-link repair 1A protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016477
Protein NameDNA cross-link repair 1A protein
Uniport IdQ6PJP8
GeneDCLRE1A
Gene Id9937
DomainDRMBL
Pfam PF07522  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:0051301 cell division
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0036297 interstrand cross-link repair
Biological Process GO:0031848 protection from non-homologous end joining at telomere
molecular function GO:0035312 5'-3' exodeoxyribonuclease activity
molecular function GO:0003684 damaged DNA binding
molecular function GO:0046872 metal ion binding
cellular component GO:0001650 fibrillar center
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-6783310 Fanconi Anemia Pathway
R-HSA-73894 DNA Repair
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1865371 BXGD016321 SEVERE COMBINED IMMUNODEFICIENCY, ATHABASKAN-TYPE
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein