Showing entry for Peripheral Neuropathy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002285
Disease NamePeripheral Neuropathy
Disease CUI IdC0031117
MeSH Codes C10  
Disease Class NameNervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O15269 BXGT004145 Serine palmitoyltransferase 1 10558 reviewed Enzyme
O15270 BXGT004146 Serine palmitoyltransferase 2 9517 reviewed Enzyme
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43323 BXGT004587 Desert hedgehog protein 50846 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75366 BXGT005116 Advillin 10677 reviewed Cellular structure
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 8989 reviewed Ion channel
O76082 BXGT005175 Solute carrier family 22 member 5 6584 reviewed Transporter
O76096 BXGT005178 Cystatin-F 8530 reviewed
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02689 BXGT005919 Myelin P2 protein 5375 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03891 BXGT006110 NADH-ubiquinone oxidoreductase chain 2 4536 reviewed
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P04156 BXGT006156 Major prion protein 5621 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10632 BXGT007592 Cytochrome P450 2C8 1558 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16157 BXGT008203 Ankyrin-1 286 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P20062 BXGT008543 Transcobalamin-2 6948 reviewed
P20618 BXGT008589 Proteasome subunit beta type-1 5689 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P25774 BXGT009066 Cathepsin S 1520 reviewed Enzyme
P27816 BXGT009209 Microtubule-associated protein 4 4134 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35270 BXGT009807 Sepiapterin reductase 6697 reviewed
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P41250 BXGT010244 Glycine--tRNA ligase 2617 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46821 BXGT010542 Microtubule-associated protein 1B 4131 reviewed Cellular structure
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49588 BXGT010713 Alanine--tRNA ligase, cytoplasmic 16 reviewed Nucleic acid binding
P49683 BXGT010726 Prolactin-releasing peptide receptor 2834 reviewed G-protein coupled receptor
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 3094 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50542 BXGT010808 Peroxisomal targeting signal 1 receptor 5830 reviewed Transporter
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P51946 BXGT010907 Cyclin-H 902 reviewed Enzyme modulator
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54577 BXGT011055 Tyrosine--tRNA ligase, cytoplasmic 8565 reviewed Enzyme
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P61626 BXGT011382 Lysozyme C 4069 reviewed
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78352 BXGT011836 Disks large homolog 4 1742 reviewed Receptor
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 2902 reviewed Ion channel
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12840 BXGT013269 Kinesin heavy chain isoform 5A 3798 reviewed Cellular structure
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q12923 BXGT013281 Tyrosine-protein phosphatase non-receptor type 13 5783 reviewed
Q13075 BXGT013308 Baculoviral IAP repeat-containing protein 1 4671 reviewed
Q13105 BXGT013311 Zinc finger and BTB domain-containing protein 17 7709 reviewed
Q13144 BXGT013317 Translation initiation factor eIF-2B subunit epsilon 8893 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14624 BXGT013491 Inter-alpha-trypsin inhibitor heavy chain H4 3700 reviewed Enzyme modulator
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15120 BXGT013542 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial 5165 reviewed Kinase
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15858 BXGT013610 Sodium channel protein type 9 subunit alpha 6335 reviewed Ion channel
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16873 BXGT013684 Leukotriene C4 synthase 4056 reviewed Enzyme
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q6PJP8 BXGT016477 DNA cross-link repair 1A protein 9937 reviewed
Q7Z2E3 BXGT017246 Aprataxin 54840 reviewed Nucleic acid binding
Q7Z406 BXGT017251 Myosin-14 79784 reviewed
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8WXF7 BXGT019011 Atlastin-1 51062 reviewed Enzyme modulator
Q92854 BXGT019385 Semaphorin-4D 10507 reviewed Signaling
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96IV0 BXGT019677 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase 55768 reviewed Enzyme
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9H015 BXGT020432 Solute carrier family 22 member 4 6583 reviewed Transporter
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H4B7 BXGT020475 Tubulin beta-1 chain 81027 reviewed Cellular structure
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial 55699 reviewed Enzyme
Q9NUV7 BXGT021217 Serine palmitoyltransferase 3 55304 reviewed Enzyme
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9NZJ4 BXGT021274 Sacsin 26278 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UH03 BXGT021690 Neuronal-specific septin-3 55964 reviewed Enzyme modulator
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y3I1 BXGT022260 F-box only protein 7 25793 reviewed
Q9Y4I1 BXGT022278 Unconventional myosin-Va 4644 reviewed Cellular structure
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q6SZW1 BXGT025034 NAD(+) hydrolase SARM1 23098 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease