Showing entry for Ectonucleotide pyrophosphatase/phosphodiesterase family member 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016569
Protein NameEctonucleotide pyrophosphatase/phosphodiesterase family member 7
Uniport IdQ6UWV6
GeneENPP7
Gene Id339221
DomainPhosphodiest
Pfam PF01663  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00600 Sphingolipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0055089 fatty acid homeostasis
Biological Process GO:0006687 glycosphingolipid metabolic process
Biological Process GO:0044241 lipid digestion
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0008156 negative regulation of DNA replication
Biological Process GO:2000304 positive regulation of ceramide biosynthetic process
Biological Process GO:0045797 positive regulation of intestinal cholesterol absorption
Biological Process GO:2000755 positive regulation of sphingomyelin catabolic process
Biological Process GO:1904729 regulation of intestinal lipid absorption
Biological Process GO:0006685 sphingomyelin catabolic process
Biological Process GO:0006684 sphingomyelin metabolic process
molecular function GO:0008081 phosphoric diester hydrolase activity
molecular function GO:0004767 sphingomyelin phosphodiesterase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005902 microvillus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1660662 Glycosphingolipid metabolism
R-HSA-428157 Sphingolipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0045817 Congo Red 650.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein