Showing entry for Kynurenine--oxoglutarate transaminase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016624
Protein NameKynurenine--oxoglutarate transaminase 3
Uniport IdQ6YP21
GeneKYAT3
Gene Id56267
DomainAminotran_1_2
Pfam PF00155  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00270 Cysteine and methionine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.6 Metabolism of other amino acids hsa00450 Selenocompound metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006103 2-oxoglutarate metabolic process
Biological Process GO:0009058 biosynthetic process
Biological Process GO:0006520 cellular amino acid metabolic process
Biological Process GO:0070189 kynurenine metabolic process
molecular function GO:0047804 cysteine-S-conjugate beta-lyase activity
molecular function GO:0047315 kynurenine-glyoxylate transaminase activity
molecular function GO:0016212 kynurenine-oxoglutarate transaminase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030170 pyridoxal phosphate binding
molecular function GO:0003723 RNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71240 Tryptophan catabolism
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005845 BXGD000341 Blood urea nitrogen measurement
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0020500 BXGD001408 Hyperoxaluria Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020501 BXGD001409 Primary Hyperoxaluria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0024517 BXGD001780 Major depression, single episode Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0231921 BXGD004530 Pulmonary function
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3160731 BXGD018470 Pulmonary function (finding)
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0043088 Pyridoxal Phosphate 247.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein