Showing entry for Cyclic GMP-AMP synthase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017928
Protein NameCyclic GMP-AMP synthase
Uniport IdQ8C6L5
GeneCgas
Gene Id214763
DomainMab-21
Pfam PF03281  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002218 activation of innate immune response
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0051607 defense response to virus
Biological Process GO:0008340 determination of adult lifespan
Biological Process GO:0006281 DNA repair
Biological Process GO:0045087 innate immune response
Biological Process GO:2000042 negative regulation of double-strand break repair via homologous recombination
Biological Process GO:0038001 paracrine signaling
Biological Process GO:0043950 positive regulation of cAMP-mediated signaling
Biological Process GO:2000774 positive regulation of cellular senescence
Biological Process GO:0010753 positive regulation of cGMP-mediated signaling
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0032481 positive regulation of type I interferon production
Biological Process GO:0050776 regulation of immune response
Biological Process GO:0002637 regulation of immunoglobulin production
Biological Process GO:0050863 regulation of T cell activation
Biological Process GO:0032479 regulation of type I interferon production
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0061501 cyclic-GMP-AMP synthase activity
molecular function GO:0003677 DNA binding
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0005525 GTP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0035861 site of double-strand break
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0024261 Adenosine Phosphate 347.06
BXGC0027925 Cpg 363.06
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein