Showing entry for 3'-5' exoribonuclease 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018339
Protein Name3'-5' exoribonuclease 1
Uniport IdQ8IV48
GeneERI1
Gene Id90459
DomainRNase_T; SAP
Pfam PF00929   PF02037  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000738 DNA catabolic process, exonucleolytic
Biological Process GO:0006259 DNA metabolic process
Biological Process GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process GO:0031047 gene silencing by RNA
Biological Process GO:0031125 rRNA 3'-end processing
Biological Process GO:0006364 rRNA processing
molecular function GO:0008408 3'-5' exonuclease activity
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0071207 histone pre-mRNA stem-loop binding
molecular function GO:0046872 metal ion binding
molecular function GO:0043022 ribosome binding
molecular function GO:0019843 rRNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0071204 histone pre-mRNA 3'end processing complex
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72312 rRNA processing
R-HSA-8868773 rRNA processing in the nucleus and cytosol
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0266294 BXGD005644 Unilateral agenesis of kidney Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0424621 BXGD008536 Body Fat Distribution
C0557874 BXGD009444 Global developmental delay
C0596887 BXGD009648 mathematical ability
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C2674737 BXGD017257 Abnormality of finger Musculoskeletal Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein