Showing entry for DAN domain family member 5



                       
General Target Information
BXGT IdBXGT018532
Protein NameDAN domain family member 5
Uniport IdQ8N907
GeneDAND5
Gene Id199699
DomainDAN
Pfam PF03045  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0003283 atrial septum development
Biological Process GO:0061371 determination of heart left/right asymmetry
Biological Process GO:0003140 determination of left/right asymmetry in lateral mesoderm
Biological Process GO:0030514 negative regulation of BMP signaling pathway
Biological Process GO:1900108 negative regulation of nodal signaling pathway
Biological Process GO:1900176 negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:0035582 sequestering of BMP in extracellular matrix
Biological Process GO:0038101 sequestering of nodal from receptor via nodal binding
Biological Process GO:0023019 signal transduction involved in regulation of gene expression
Biological Process GO:0003281 ventricular septum development
molecular function GO:0016015 morphogen activity
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-1181150 Signaling by NODAL
R-HSA-1266738 Developmental Biology
R-HSA-1433617 Regulation of signaling by NODAL
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0149871 BXGD003375 Deep Vein Thrombosis Cardiovascular Diseases
C0152021 BXGD003520 Congenital heart disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein