Showing entry for Congenital heart disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003520
Disease NameCongenital heart disease
Disease CUI IdC0152021
MeSH Codes C16   C14  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00439 BXGT005539 Phenylalanine-4-hydroxylase 5053 reviewed
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07814 BXGT006680 Bifunctional glutamate/proline--tRNA ligase 2058 reviewed Enzyme
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21333 BXGT008638 Filamin-A 2316 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P30533 BXGT009434 Alpha-2-macroglobulin receptor-associated protein 4043 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A 657 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63165 BXGT011506 Small ubiquitin-related modifier 1 7341 reviewed
P69891 BXGT011646 Hemoglobin subunit gamma-1 3047 reviewed
P78563 BXGT011850 Double-stranded RNA-specific editase 1 104 reviewed Enzyme
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q14524 BXGT013478 Sodium channel protein type 5 subunit alpha 6331 reviewed Ion channel
Q14623 BXGT013490 Indian hedgehog protein 3549 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q7Z494 BXGT017254 Nephrocystin-3 27031 reviewed
Q8N3J5 BXGT018506 Protein phosphatase 1K, mitochondrial 152926 reviewed Enzyme
Q8N907 BXGT018532 DAN domain family member 5 199699 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UH77 BXGT021692 Kelch-like protein 3 26249 reviewed
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
P20809 BXGT025043 Interleukin-11 3589 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease