Showing entry for Estradiol 17-beta-dehydrogenase 11


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018542
Protein NameEstradiol 17-beta-dehydrogenase 11
Uniport IdQ8NBQ5
GeneHSD17B11
Gene Id51170
Domainadh_short
Pfam PF00106  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006710 androgen catabolic process
Biological Process GO:0006703 estrogen biosynthetic process
molecular function GO:0004303 estradiol 17-beta-dehydrogenase activity
molecular function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
molecular function GO:0016229 steroid dehydrogenase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005811 lipid droplet
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-193144 Estrogen biosynthesis
R-HSA-196071 Metabolism of steroid hormones
R-HSA-556833 Metabolism of lipids
R-HSA-8957322 Metabolism of steroids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424678 BXGD008537 Lean body mass
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein