Showing entry for Hyaluronidase-2



                       
General Target Information
BXGT IdBXGT018758
Protein NameHyaluronidase-2
Uniport IdQ8SQG8
GeneHYAL2
Gene Id281838
DomainGlyco_hydro_56
Pfam PF01630  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0051216 cartilage development
Biological Process GO:0044344 cellular response to fibroblast growth factor stimulus
Biological Process GO:0071347 cellular response to interleukin-1
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0071493 cellular response to UV-B
Biological Process GO:0051607 defense response to virus
Biological Process GO:0019064 fusion of virus membrane with host plasma membrane
Biological Process GO:0006027 glycosaminoglycan catabolic process
Biological Process GO:0002244 hematopoietic progenitor cell differentiation
Biological Process GO:0030214 hyaluronan catabolic process
Biological Process GO:0042117 monocyte activation
Biological Process GO:0010259 multicellular organism aging
Biological Process GO:0060586 multicellular organismal iron ion homeostasis
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0010764 negative regulation of fibroblast migration
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:0061099 negative regulation of protein tyrosine kinase activity
Biological Process GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0042307 positive regulation of protein import into nucleus
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0035810 positive regulation of urine volume
Biological Process GO:0070295 renal water absorption
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0000302 response to reactive oxygen species
Biological Process GO:0009615 response to virus
Biological Process GO:0048705 skeletal system morphogenesis
Biological Process GO:0019087 transformation of host cell by virus
Biological Process GO:0046718 viral entry into host cell
molecular function GO:0005540 hyaluronic acid binding
molecular function GO:0033906 hyaluronoglucuronidase activity
molecular function GO:0004415 hyalurononglucosaminidase activity
molecular function GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0050431 transforming growth factor beta binding
molecular function GO:0001618 virus receptor activity
cellular component GO:0031362 anchored component of external side of plasma membrane
cellular component GO:0046658 anchored component of plasma membrane
cellular component GO:0016324 apical plasma membrane
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0030139 endocytic vesicle
cellular component GO:0005764 lysosome
cellular component GO:0045121 membrane raft
cellular component GO:0005902 microvillus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000764 L-Ascorbic acid 176.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein